Monday, 10th February 50th Lorne Proteins Conference 2025
Session 3 - Joint Session with Australian Proteomics Society
8:30AM - 10:30AM
Monday, 10th February
Heritage Ballroom
Chairs: & Danny Hatters
- What do we know about (your) antibodies?: Novel insights from mass spectrometry - Albert Heck
- Deciphering Dysregulated Molecular Pathways in Huntington's Disease: The Role of HTT in DNA Mismatch Repair - Christian Makhoul
- FUT10 and FUT11 are novel protein O-fucosyltransferases that modify protein EMI domains - Mark Larance
- Mechanisms of Pyruvate Kinase Allosteric Regulation by CryoEM and HDX-MS - Sheena D'Arcy Ph.D.
Morning Tea/Coffee Break
10:30AM - 11:00AM
Monday, 10th February
Convention Centre
Session 4 - Sparrow Session
11:00AM - 1:00PM
Monday, 10th February
Heritage Ballroom
Chairs: Melissa Call & Fiona Whelan
- Insecticidal proteins from ferns resemble Bacillus thuringiensis toxins - Megan J Maher
- LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR - Andrew Ellisdon
- USING CRYO-ELECTRON MICROSCOPY TO UNDERSTAND THE BIOLOGY AND DRUG BINDING OF THE WNT SIGNALLING PATHWAY - Alisa Glukhova
- A PPR protein-based FRET sensor for RNA - Charles S Bond
Lunch
1:00PM - 2:00PM
Monday, 10th February
Convention Centre
Student Lunch
1:00PM - 2:00PM
Monday, 10th February
Mantra Restaurant
Poster Session A
4:00PM - 6:00PM
Monday, 10th February
Convention Centre
- A universal rapid test for protein-nucleic acid interactions - Casey Toft
- High-affinity PQQ import is widespread in gram-negative bacteria - Fabian Munder
- Deciphering the essential complexity of mitochondrial Signal Transducer and Activator of Transcription 3 (STAT3) biology - Nelson / Sibo NY Yu
- Exploiting cancers metabolism: A structural focus on malic enzyme inhibitor NPD-389 using structural-based drug design. - Ben Krinkel
- Immunogenic HLA-B*44:03 restricted peptide does not induce the same response in individuals with B*44 superfamily molecules - Samuel Liwei Leong
- Structural characterisation of the interactions between the SIN3 PAH domains and their binding partners - Bhagya Mendis
- A molecular twist: Unveiling formate binding in a predicted amino acid binding protein in marine picocyanobacteria. - Anushka Vidurangi Samaraweera
- When Necroptosis meets Protein Liquid-liquid Phase Separation - Tianchen Li
- Flexible and contractile Herelleviridae bacteriophage JS1 showing cross-species activity against Staphylococci - Sabrina Suhani
- PmxPred: A data-driven approach for the identification of active polymyxin analogues against gram-negative bacteria - Xiaoyu Wang
- Mechanism of CD8+ T cell cross-reactivity to SARS-CoV-2 and seasonal coronaviruses epitopes - You Min Ahn
- Epitope-anchored contrastive transfer learning for paired CD8+ T cell receptor–antigen recognition - Yumeng Zhang
- Understanding the Ubiquitination and Characterisation of the Atypical Kinase RIOK3 - Jacqueline J.L Ormsby
- Harnessing AlphaFold and explainable AI to better characterise human missense variants and diseases - Qisheng Pan
- Towards a selective insecticide against the green peach aphid - Simone Titterton
- A PaRTI at the FunCyDisCo – Expression of Cysteine-Rich Myrtle Rust Effector Proteins in E. coli Using a Coexpression System - Jovarn Sullivan
- Thiolate oxidation of the p18INK4c tumour suppressor protein induces its transition into amyloid structures. - Emilie M. Hamzah
- Investigation of the interaction between gating modifier toxins and voltage-gated ion channels using cyclised nanodiscs - Yifei Zhu
- Structure and function of the novel endolysin, PA3 - Mackenzie Aitken
- Understanding the molecular structure and signalling functions of Eph receptor pseudokinase EphA10 - Emily C Park
- Uncovering the differential function and expression of DCLK1 isoforms in aggressive cancers - Lyn R. Deng
- Structural and functional characterisation of novel piezo1 mutations causing hydrops fetalis - Zhou Yi Wang
- How does size affect the affinities of peptide ligands discovered via mRNA display? - Xuefei Jing
- Therapeutic targeting of proteins involved in Toll-like receptor signalling - Vishal Pandey
- Can we generate ligands selectively binding integral membrane protein? - Junyu Liu
- Lost in space: Radiation-triggered fibril formation of p16INK4a aboard the International Space Station - Shelby G Gray
- Cyclic peptides as novel probes to study the RIPK3 RHIM functional amyloid - Jessica Buchanan
- Ultrasonication-Enhanced β2-Microglobulin Amyloid Formation: Effects of Temperature and Salt on Folding and Misfolding - Tomoki Ota
- Determining How Lectin-Like Antibiotics Kill Pseudomonas spp. Using Proteomics and Phenotypic Analysis - Imogen Samuels
- AI-designed protein inhibitors can block heme uptake and inhibit growth of pathogenic E. coli - Daniel R. Fox
- Tailoring tailocins: development of a recombinant expression system for modular phage tail–like bacteriocins - Jose Benjamin P. Dar Juan
- Towards the development of Safer Ecofriendly Selective Pesticides to safeguard honeybees - SHAHNAZ SULTANA
- Novel peptide-based inhibitors of protein kinase Cε interactions for the treatment of type 2 diabetes mellitus - Abisola A Siedoks
- Unveiling the Versatility of the Thioredoxin Framework: Insights from the Structural Examination of Francisella tularensis DsbA1. - Stephanie Penning
- Integrative Bioinformatic Approach to Identify Gluten-Degrading Proteins in the Gut Microbiome: Uncovering Microbial Enzymes with Therapeutic Potential for Celiac Disease - Peter Prendergast
- Prediction of the toxicity of proteins and peptides by exploiting structural information based on deep learning - Jing J Xu
- Further insights into asymptomatic outcome after SARS-CoV-2 in HLA-B*15:01+ individuals - Lawton Murdolo
- Characterise the COMMD-like Proteins from Bacteria and Archaea - Meihan Liu
- Insights into the mechanism of the Streptococcus pneumoniae glutathione import system - Sarah E du Toit
- Expanding substrate diversity of O-fucosylation through structural alignment and glycoproteomics - Benjamin Eberand
- Expanding the Redox Response: Crosstalk Between Dsb and Scs Systems in Klebsiella pneumoniae - Callum O'Flaherty
- Investigating the role of the hydrophilic loop in the oligomerisation and activation of VacA - William Elliott
- Monitoring the Oxidation-Induced Amyloid State of Tumour Suppressor Protein p16ᴵᴺᴷ⁴ᵃ in human cell culture - Alex Botha
- Elucidating the mechanism of action of a small molecule endocytosis inhibitor - Philip Zhong
- Respiratory chain coupling proteins: A novel and widespread mechanism for microbial quinone reduction - Ashleigh Kropp
- Identification of Rab GTPase interacting partners using AlphaFold2 - Denaye Eldershaw
- Investigating T cell responses to a nested peptide - Georgia Dow
- EXPLORING PROTEIN INTERACTIONS BETWEEN ENVIRONMENTAL KLEBSIELLA AND THE BACTERIOPHAGES THAT RECOGNIZE THEM - Alex Hall
- A modular vector system for baculovirus expression streamlines the production of large protein complexes - Zhihao Lai
- Decoding PLD3: Structural and functional discoveries with therapeutic potential for Alzheimer’s Disease - Maria Eleni Georgopoulou
- Looking deeper into outer membrane porin loss and resistance to β-lactam drugs including carbapenems in Klebsiella pneumoniae. - Jiahui Li
- Analytical ultracentrifugation: Old dog, new tricks - Zachary D Tillett
- RNA Substrate Recognition by CRISPR-Cas13 HEPN Nucleases - Roland W Calvert
- Structure and function of NanU, an extracellular neuraminate uptake protein in gram-negative bacteria - Ruosong Zhang
- Developing a biosensor to map the interactome of CaMK4: An emerging therapeutic target for profound Autism spectrum disorders - Bethany Lei
- Structural characterization of INPP4B: insights into the final unsolved human phosphoinositide phosphatase family - Gareth D Jones
- Structural and Functional Insights into Substrate Recognition by the Bacterial Virulence Regulator DsbA - Taylor Cunliffe
- Exploiting tau amyloid polymorphism for diagnosis of Chronic Traumatic Encephalopathy (CTE) - Joanna L New
- Breaching the cell wall: How phages enter their DNA through the peptidoglycan layer. - Kishani Naligama
Session 5 - Anders Early Career Award
7:45PM - 9:05PM
Monday, 10th February
Heritage Ballroom
Chairs: Bostjan Kobe & Erinna Lee
Sponsored by:
- The Commander Complex: A Comprehensive Analysis. - Michael Healy
- Structural basis of toxin delivery by the Type VI Secretion System. - Brooke K Hayes
- Dissecting GPCR function through nanodiscs; structural and pharmacological approaches - Wessel A C Burger
- Mechanical activation of OSCA channels opens a lipid lined pore - Ruitao Jin
Poster Session B
9:00PM - 10:00PM
Monday, 10th February
Convention Centre
- Molecular mechanisms of lipid antigen presentation to T cells in protective or aberrant immunity - Adam Shahine
- A peptidic molecular glue exploits differences in protein dynamics to drive high paralogue selectivity among BET-family bromodomains - Joel Mackay
- Unconventional Secretion and Activity of SARS-CoV-2 Main Protease (3CLpro) by Caspase and 3CLpro Activation of Gasdermin D Pore Formation - Chris Overall
- Reconstitution of ACE2-S1-RBD interaction on supported lipid bilayer reveals endocytosis-mediated Omicron S1-RBD internalization - Angelin Philip
- Picking up the PACE: Structural characterisation of a novel PACE efflux pump - Bhumika S Shah
- Insights into the SH2 domain involved in JAK/STAT/SOCS cascade - Yuntong Wu
- Silence is Golden: How is quiescence regulated in Klebsiella and what is the significance of quiescent porins in AMR? - Kwok Jian Goh
- MMS EVALUATION OF HOS FOR IGG SAMPLES SPIKED WITH BSA - Peter Davis
- Functional Ambidexterity of an Ancient Nucleic Acid-Binding Domain - Yael Dr Fridmann Sirkis
- The association and molecular mechanism behind asymptomatic SARS-CoV-2 infection - Dimitra SM Chatzileontiadou
- Structural Insights into A Novel Chi-like Phage Targeting Multiple Klebsiella spp. - Yan Li
- A novel conformation-specific BAK antibody enables assessment of non-activated BAK levels in cancer cells - Michelle Miller
- Investigating phosphorylation-dependent interactions between JAKs and PTP1B - Hao Chen
- Investigating complex molecular interactions using novel SPR analysis approaches - Emma Dal Maso
- TEMPO: Training in Electron Microscopy Processing and Optics - Joshua M Hardy
- How does intra-protein motion influence protein function? Cryptochrome magnetoreception and cryptophyte light-harvesting - Gesa Gruening
- TFold for accurate peptide-HLA structure prediction - Janesha Maddumage
- Molecular Mechanisms of Genome Replication in Emerging RNA Viruses - Jeremy R. Keown
- How is the bacterial flagellar secreted through the Gram-positive S-layer? - Christopher Stubenrauch
- Structure-function analysis of an understudied type of lytic polysaccharide monooxygenase. - Kelsi R. Hall
- Native mass spectrometry prescreening of G protein-coupled receptor complexes for cryo-EM structure determination - Weijing Liu
- Using minicells to examine the β-barrel protein arrays of Klebsiella pneumoniae - Cara Press
- Measuring interactions between synthetic TM domains in live cell membranes for CAR-T cell immunotherapy development - Colin Hockings
- Mechanical activation of OSCA channels opens a lipid lined pore - Ruitao Jin
- Mechanisms of amyloid fibril formation under ultrasonication using HANABI - Keiichi Yamaguchi
- Now I'm amyloid, now I'm not - A single redox switch controls structure and function of a tumour suppressor protein family - Christoph Goebl
- TRADING TAILS: Identification of native protein scaffolds leading to the engineering of designer bacteriophages. - Rhys Dunstan
- Structural investigation of allosteric modulation of the delta opioid receptor - Jesse I Mobbs
- How similar are protein crystallisation conditions? A Data-Driven Approach Using Deep Metric Learning. - Nicholas Rosa
- Enhancing the stability of the SOCS2 SH2 domain in a ligand-independent manner - Cyrus Tan
- On developing hidden Markov models using a structural alphabet - Ashar Malik
- A structural basis of allosteric ligand selectivity at GPCRs - David M Thal